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1

A simple, cheap but reliable method for evaluation of zinc chelating properties

Carmen Catapano, Maria, Tvrdý, Václav, Karlíčková, Jana, Mercolini, Laura, Mladěnka, Přemysl

Journal:

Bioorganic Chemistry

Year:

2018

Language:

english

File:

PDF, 987 KB

english, 2018

2

Is a Highly Linear Relationship Between the Dose of Quercetin and the Pharmacological Effect Possible? — A Comment on Liu, et al. Evaluation of Antioxidant and Immunity Activities of Quercetin in Isoproterenol-Treated Rats. Molecules 2012, 17, 4281–4291

Mladěnka, Přemysl, Hrdina, Radomír, Filipský, Tomáš, Říha, Michal, Palicka, Vladimir

Journal:

Year:

2014

Language:

english

File:

PDF, 257 KB

english, 2014

3

Antiplatelet Effects of Flavonoids Mediated by Inhibition of Arachidonic Acid Based Pathway

Karlíčková, Jana, Říha, Michal, Filipský, Tomáš, Macáková, Kateřina, Hrdina, Radomír, Mladěnka, Přemysl

Journal:

Year:

2015

Language:

english

File:

PDF, 307 KB

english, 2015

4

In vitro analysis of iron chelating activity of flavonoids

Přemysl Mladěnka, Kateřina Macáková, Tomáš Filipský, Libuše Zatloukalová, Luděk Jahodář, Paolo Bovicelli, Ilaria Proietti Silvestri, Radomír Hrdina, Luciano Saso

Journal:

Journal of Inorganic Biochemistry

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

5

Comprehensive review of cardiovascular toxicity of drugs and related agents

Mladěnka, Přemysl, Applová, Lenka, Patočka, Jiří, Costa, Vera Marisa, Remiao, Fernando, Pourová, Jana, Mladěnka, Aleš, Karlíčková, Jana, Jahodář, Luděk, Vopršalová, Marie, Varner, Kurt J., Štěrba, Mar

Journal:

Medicinal Research Reviews

Year:

2018

Language:

english

File:

PDF, 2.61 MB

english, 2018

6

In vitro interactions of coumarins with iron

Přemysl Mladěnka, Kateřina Macáková, Libuše Zatloukalová, Zuzana Řeháková, Brajendra K. Singh, Ashok K. Prasad, Virinder S. Parmar, Luděk Jahodář, Radomír Hrdina, Luciano Saso

Journal:

Year:

2010

Language:

english

File:

PDF, 455 KB

english, 2010

7

Simultaneous determination of the novel thiosemicarbazone anti-cancer agent, Bp4eT, and its main phase I metabolites in plasma: Application to a pilot pharmacokinetic study in rats

Stariat, Ján, Suprunová, Vlasta, Roh, Jaroslav, Šesták, Vít, Eisner, Tomáš, Filipský, Tomáš, Mladěnka, Přemysl, Nobilis, Milan, Šimůnek, Tomáš, Klimeš, Jiří, Kalinowski, Danuta S., Richardson, Des R.,

Journal:

Biomedical Chromatography

Year:

2014

Language:

english

File:

PDF, 382 KB

english, 2014

8

Direct administration of rutin does not protect against catecholamine cardiotoxicity

Přemysl Mladěnka, Libuše Zatloukalová, Tomáš Šimůnek, Zuzana Bobrovová, Vladimír Semecký, Petr Nachtigal, Pavlína Hašková, Eliška Macková, Jaroslava Vávrová, Magdaléna Holečková, Vladimir Palicka, Rad

Journal:

Year:

2009

Language:

english

File:

PDF, 1.53 MB

english, 2009

9

The influence of iron chelators on myocardial metal content after catecholamine cardiotoxic insult

Přemysl Mladěnka, Vladimír Semecký, Zuzana Bobrovová, Veronika Filipová, Libuše Zatloukalová, Radomír Hrdina

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2008

Language:

english

File:

PDF, 141 KB

english, 2008

10

The role of reactive oxygen and nitrogen species in cellular iron metabolism

MLADĚNKA, PŘEMYSL, ŠIMŮNEK, TOMÁŠ, HÜBL, MOJMÍR, HRDINA, RADOMÍR

Journal:

Free Radical Research

Year:

2006

Language:

english

File:

PDF, 195 KB

english, 2006

11

Isoflavones Reduce Copper with Minimal Impact on Iron In Vitro

Karlíčková, Jana, Macáková, Kateřina, Říha, Michal, Pinheiro, Liliane Maria Teixeira, Filipský, Tomáš, Horňasová, Veronika, Hrdina, Radomír, Mladěnka, Přemysl

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2015

Language:

english

File:

PDF, 1.85 MB

english, 2015

12

Correction to: Interaction of soy isoflavones and their main metabolites with hOATP2B1 transporter

Navrátilová, Lucie, Applová, Lenka, Horký, Pavel, Mladěnka, Přemysl, Pávek, Petr, Trejtnar, František

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2018

Language:

english

File:

PDF, 284 KB

english, 2018

13

The effects of lactoferrin in a rat model of catecholamine cardiotoxicity

Přemysl Mladěnka, Vladimír Semecký, Zuzana Bobrovová, Petr Nachtigal, Jaroslava Vávrová, Magdaléna Holečková, Vladimir Palicka, Yvona Mazurová, Radomír Hrdina

Journal:

Year:

2009

Language:

english

File:

PDF, 336 KB

english, 2009

14

Interaction of soy isoflavones and their main metabolites with hOATP2B1 transporter

Navrátilová, Lucie, Applová, Lenka, Horký, Pavel, Mladěnka, Přemysl, Pávek, Petr, Trejtnar, František

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

15

The influence of microbial isoflavonoid specific metabolites on platelets and transition metals iron and copper

Migkos, Thomas, Applová, Lenka, Horký, Pavel, Tvrdý, Václav, Karlíčková, Jana, Macáková, Kateřina, Hrubša, Marcel, Catapano, Maria Carmen, Tomanek, Magdalena, Pour, Milan, Mladěnka, Přemysl

Journal:

Year:

2019

Language:

english

File:

PDF, 1.40 MB

english, 2019

16

In vitro characteristics of 1-phenyl-3-methyl-4-acylpyrazol-5-ones iron chelators

Tomáš Filipský, Přemysl Mladěnka, Kateřina Macáková, Radomír Hrdina, Luciano Saso, Fabio Marchetti, Claudio Pettinari

Journal:

Year:

2012

Language:

english

File:

PDF, 697 KB

english, 2012

17

In vitro copper-chelating properties of flavonoids

Ríha, Michal, Karlícková, Jana, Filipský, Tomáš, Jahodár, Ludek, Hrdina, Radomír, Mladenka, Premysl

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 63 KB

english, 2014

18

Iron reduction potentiates hydroxyl radical formation only in flavonols

Kateřina Macáková, Přemysl Mladěnka, Tomáš Filipský, Michal Říha, Luděk Jahodář, František Trejtnar, Paolo Bovicelli, Ilaria Proietti Silvestri, Radomír Hrdina, Luciano Saso

Journal:

Year:

2012

Language:

english

File:

PDF, 886 KB

english, 2012

19

Mathematical calculations of iron complex stoichiometry by direct UV–Vis spectrophotometry

Filipský, Tomáš, Říha, Michal, Hrdina, Radomír, Vávrová, Kateřina, Mladěnka, Přemysl

Journal:

Bioorganic Chemistry

Year:

2013

Language:

english

File:

PDF, 1.05 MB

english, 2013

20

Aqueous injection of quercetin: An approach for confirmation of its direct in vivo cardiovascular effects

Porcu, Elena Piera, Cossu, Massimo, Rassu, Giovanna, Giunchedi, Paolo, Cerri, Guido, Pourová, Jana, Najmanová, Iveta, Migkos, Thomas, Pilařová, Veronika, Nováková, Lucie, Mladěnka, Přemysl, Gavini, El

Journal:

International Journal of Pharmaceutics

Year:

2018

Language:

english

File:

PDF, 842 KB

english, 2018

21

Marine Ligands of the Pregnane X Receptor (PXR): An Overview

Carazo, Alejandro, Mladěnka, Přemysl, Pávek, Petr

Journal:

Year:

2019

Language:

english

File:

PDF, 1.77 MB

english, 2019

22

The relationship of oxidative stress markers and parameters of myocardial function in a rat model of cardiotoxicity

Mladenka, Premysl, Filipský, Tomáš, Ríha, Michal, Vávrová, Jaroslava, Holecková, Magdalena, Palicka, Vladimir, Hrdina, Radomír

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 57 KB

english, 2014

23

Effect of novel 1-phenyl-3-methyl-4-acylpyrazolones on iron chelation and Fenton reaction

Filipský, Tomáš, Mladenka, Premysl, Macáková, Katerina, Hrdina, Radomír, Saso, Luciano, Marchetti, Fabio, Pettinari, Claudio

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 77 KB

english, 2014

24

Cardiovascular effects of flavonoids are not caused only by direct antioxidant activity

Přemysl Mladěnka, Libuše Zatloukalová, Tomáš Filipský, Radomír Hrdina

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 590 KB

english, 2010

25

Novel method for rapid copper chelation assessment confirmed low affinity of D-penicillamine for copper in comparison with trientine and 8-hydroxyquinolines

Říha, Michal, Karlíčková, Jana, Filipský, Tomáš, Macáková, Kateřina, Hrdina, Radomír, Mladěnka, Přemysl

Journal:

Journal of Inorganic Biochemistry

Year:

2013

Language:

english

File:

PDF, 1000 KB

english, 2013

26

The isoflavonoid tectorigenin has better antiplatelet potential than acetylsalicylic acid

Applová, Lenka, Karlíčková, Jana, Říha, Michal, Filipský, Tomáš, Macáková, Kateřina, Spilková, Jiřina, Mladěnka, Přemysl

Journal:

Year:

2017

Language:

english

File:

PDF, 600 KB

english, 2017

27

Interrelationships of functional, biochemical and morphological variables in catecholamine cardiotoxicity

Přemysl Mladěnka, Radek Hrdina, Zuzka Bobrovová, Mojmír Hübl, Petr Nachtigal, Jan Škrle, Vladimir Semecký

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

28

Interaction of isolated silymarin flavonolignans with iron and copper

Tvrdý, Václav, Catapano, Maria Carmen, Rawlik, Tomasz, Karlíčková, Jana, Biedermann, David, Křen, Vladimír, Mladěnka, Přemysl, Valentová, Kateřina

Journal:

Journal of Inorganic Biochemistry

Year:

2018

Language:

english

File:

PDF, 1.47 MB

english, 2018

29

An Original HPLC Method with Coulometric Detection to Monitor Hydroxyl Radical Generation via Fenton Chemistry

Catapano, Maria Carmen, Protti, Michele, Fontana, Tommaso, Mandrioli, Roberto, Mladěnka, Přemysl, Mercolini, Laura

Journal:

Year:

2019

Language:

english

File:

PDF, 1.02 MB

english, 2019

30

Vasodilatory activity of human quercitin metabolites

Najmanová, Iveta, Vopršálová, Marie, Mladenka, Premysl

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 67 KB

english, 2014

31

Flavonoid metabolite 3-(3-hydroxyphenyl)propionic acid formed by human microflora decreases arterial blood pressure in rats

Najmanová, Iveta, Pourová, Jana, Vopršalová, Marie, Pilařová, Veronika, Semecký, Vladimír, Nováková, Lucie, Mladěnka, Přemysl

Journal:

Molecular Nutrition & Food Research

Year:

2016

Language:

english

File:

PDF, 897 KB

english, 2016

32

The Stoichiometry of Isoquercitrin Complex with Iron or Copper Is Highly Dependent on Experimental Conditions

Catapano, Maria, Tvrdý, Václav, Karlíčková, Jana, Migkos, Thomas, Valentová, Kateřina, Křen, Vladimír, Mladěnka, Přemysl

Journal:

Year:

2017

Language:

english

File:

PDF, 2.15 MB

english, 2017

33

Lanthanide(III) complexes are more active inhibitors of the Fenton reaction than pure ligands

Martin, Jan, Mladěnka, Přemysl, Saso, Luciano, Kostova, Irena

Journal:

Year:

2015

Language:

english

File:

PDF, 289 KB

english, 2015

34

Inhibitory Effects of Quercetin and Its Human and Microbial Metabolites on Xanthine Oxidase Enzyme

Mohos, Violetta, Pánovics, Attila, Fliszár-Nyúl, Eszter, Schilli, Gabriella, Hetényi, Csaba, Mladěnka, Přemysl, Needs, Paul W., Kroon, Paul A., Pethő, Gábor, Poór, Miklós

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 3.29 MB

english, 2019

35

Dexrazoxane provided moderate protection in a catecholamine model of severe cardiotoxicity

Zatloukalová, Libuše, Filipský, Tomáš, Mladěnka, Přemysl, Semecký, Vladimír, Macáková, Kateřina, Holečková, Magdalena, Vávrová, Jaroslava, Palicka, Vladimir, Hrdina, Radomír

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

2012

File:

PDF, 1.80 MB

2012

36

Amino acid derivatives as transdermal permeation enhancers

Janůšová, Barbora, Školová, Barbora, Tükörová, Katarína, Wojnarová, Lea, Šimůnek, Tomáš, Mladěnka, Přemysl, Filipský, Tomáš, Říha, Michal, Roh, Jaroslav, Palát, Karel, Hrabálek, Alexandr, Vávrová, Kat

Journal:

Journal of Controlled Release

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

37

Applicability of the OECD 455 in-vitro assay for determination of hERa agonistic activity of isoflavonoids

Gramec Skledar, Darja, Tvrdý, Václav, Kenda, Maša, Zega, Anamarija, Pour, Milan, Horký, Pavel, Mladěnka, Přemysl, Sollner Dolenc, Marija, Peterlin Mašič, Lucija

Journal:

Toxicology and Applied Pharmacology

Year:

2020

File:

PDF, 1.51 MB

2020

38

In vitro platelet antiaggregatory properties of 4-methylcoumarins

Macáková, Kateřina, Řeháková, Zuzana, Mladěnka, Přemysl, Karlíčková, Jana, Filipský, Tomáš, Říha, Michal, Prasad, Ashok K., Parmar, Virinder S., Jahodář, Luděk, Pávek, Petr, Hrdina, Radomír, Saso, Luc

Journal:

Year:

2012

Language:

english

File:

PDF, 484 KB

english, 2012

39

The current clinical knowledge on the treatment of gambling disorder: A summary

Hloch, Karel, Mladěnka, Přemysl, Doseděl, Martin, Adriani, Walter, Zoratto, Francesca

Journal:

Year:

2017

Language:

english

File:

PDF, 695 KB

english, 2017

40

In vitro evaluation of copper-chelating properties of flavonoids

Říha, Michal, Karlíčková, Jana, Filipský, Tomáš, Macáková, Kateřina, Rocha, Liliana, Bovicelli, Paolo, Silvestri, Ilaria Proietti, Saso, Luciano, Jahodář, Luděk, Hrdina, Radomír, Mladěnka, Přemysl

Journal:

Year:

2014

Language:

english

File:

PDF, 476 KB

english, 2014

41

LC–UV/MS methods for the analysis of prochelator—Boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH)

Bureš, Jan, Jansová, Hana, Stariat, Ján, Filipský, Tomáš, Mladěnka, Přemysl, Šimůnek, Tomáš, Kučera, Radim, Klimeš, Jiří, Wang, Qin, Franz, Katherine J., Kovaříková, Petra

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2015

Language:

english

File:

PDF, 553 KB

english, 2015

42

Simultaneous determination of quercetin and its metabolites in rat plasma by using ultra-high performance liquid chromatography tandem mass spectrometry

Pilařová, Veronika, Plachká, Kateřina, Chrenková, Lucia, Najmanová, Iveta, Mladěnka, Přemysl, Švec, František, Novák, Ondřej, Nováková, Lucie

Journal:

Year:

2018

Language:

english

File:

PDF, 1.26 MB

english, 2018

43

Fruit extracts of 10 varieties of elderberry (Sambucus nigra L.) interact differently with iron and copper

Mladěnka, Přemysl, Říha, Michal, Martin, Jan, Gorová, Barbora, Matějíček, Aleš, Spilková, Jiřina

Journal:

Phytochemistry Letters

Year:

2016

Language:

english

File:

PDF, 1.15 MB

english, 2016

44

O31 Can colonic metabolites be responsible for the hypotensive effect of orally given quercetin?

Mladenka, Premysl, Najmanova, Iveta, Pourova, Jana, Migkos, Thomas, Vopršalová, Marie

Journal:

Biochemical Pharmacology

Year:

2017

Language:

english

File:

PDF, 81 KB

english, 2017

45

Mono and dihydroxy coumarin derivatives: Copper chelation and reduction ability

Catapano, Maria Carmen, Karlíčková, Jana, Tvrdý, Václav, Sharma, Sweta, Prasad, Ashok K., Saso, Luciano, Chhillar, Anil K., Kuneš, Jiří, Pour, Milan, Parmar, Virinder S., Mladěnka, Přemysl

Journal:

Journal of Trace Elements in Medicine and Biology

Year:

2018

Language:

english

File:

PDF, 865 KB

english, 2018

46

Two flavonoid metabolites, 3,4-dihydroxyphenylacetic acid and 4-methylcatechol, relax arteries ex vivo and decrease blood pressure in vivo

Pourová, Jana, Najmanová, Iveta, Vopršalová, Marie, Migkos, Thomas, Pilařová, Veronika, Applová, Lenka, Nováková, Lucie, Mladěnka, Přemysl

Journal:

Vascular Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.11 MB

english, 2018

47

HEMATOXYLIN ASSAY OF CUPRIC CHELATION CAN GIVE FALSE POSITIVE RESULTS

Macáková, Kateřina, Catapano, Maria Carmen, Tvrdý, Václav, Klimková, Kateřina, Karlíčková, Jana, Mladěnka, Přemysl

Journal:

Journal of Trace Elements in Medicine and Biology

Year:

2018

Language:

english

File:

PDF, 1.02 MB

english, 2018

48

4‐Methylcatechol, a Flavonoid Metabolite with Potent Antiplatelet Effects

Applová, Lenka, Karlíčková, Jana, Warncke, Paul, Macáková, Kateřina, Hrubša, Marcel, Macháček, Miloslav, Tvrdý, Václav, Fischer, Dagmar, Mladěnka, Přemysl

Journal:

Molecular Nutrition & Food Research

Year:

2019

File:

PDF, 1.67 MB

2019

49

Parameters of oxidative stress status in healthy subjects: their correlations and stability after sample collection

Omidreza Firuzi, Přemysl Mladěnka, Valeria Riccieri, Antonio Spadaro, Rita Petrucci, Giancarlo Marrosu, Luciano Saso

Journal:

Journal of Clinical Laboratory Analysis

Year:

2006

Language:

english

File:

PDF, 174 KB

english, 2006

50

4‐Methylcatechol, a Flavonoid Metabolite with Potent Antiplatelet Effects

Applová, Lenka, Karlíčková, Jana, Warncke, Paul, Macáková, Kateřina, Hrubša, Marcel, Macháček, Miloslav, Tvrdý, Václav, Fischer, Dagmar, Mladěnka, Přemysl

Journal:

Molecular Nutrition & Food Research

Year:

2019

Language:

english

File:

PDF, 1.67 MB

english, 2019

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